The Bioinformatics Image Core provides services for researchers from various areas in cell biology and analysis of large data sets from high-throughput screening experiments.
The Bioinformatics Image Core (BIONIC) facility supports:
- the high-throughput screening activities at the Translational Research Resource Centre
- the image processing and data analysis throughout the CBU/LMCB
Advanced microscopic technology is allowing imaging approaches to detect cellular dynamics with increasing spatial and temporal resolution. New approaches are required to allow effective analysis and quantitation of the data,requiring individuals with advanced skills in image analysis and computing.
The core facility has experience in image analysis, statistical methods for analyzing large data sets and experience in automation processes. as well as a good understanding of genomic technologies and the drug discovery process. We have experience in operation of PerkinElmer Opera high-content screening microscope. The core's activity is based on image analysis softwares ImageJ and Acapella as well as the statistical program R with Bioconductor packagessuch as CellHTS2. Furthermore, we have some experience in tissue culture and basic laboratory techniques.
Equipment of the Bioinformatics Image Core
 | ASUS Server Z8PE-D18 144 GB memory 2x Quad-Core Intel® Xeon® E5520 CPUs (16 cores) Corsair Hydro H50 High Performance Liquid CPU Cooler NVidia Quadro FX3800 Linux Kubuntu 12.04 |  |
| Tyan FT48-B8812 High Performance Barebone System 256 GB memory 4x 12-Core AMD® Opteron® 6174 CPUs (48 cores) NVidia GeForce GTX 580 Acer GN245HQ 3D monitor with NVidia 3D Vision Linux 2.6.35 |
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